If you do notice a change, and it continues for an extended period of time despite dietary changes, you should see your GP to find out if there is anything they can suggest to help with your situation. Hot beverages – whilst we all tend to enjoy a tea or coffee as a refreshment or pick-me-up, they do have a diuretic effect. Diuretics increase the production of urine, meaning we have to visit the loo more than usual. Bear this in mind when drinking coffee to help encourage a movement. “It’s one of my favorites when I’m doing a detox because it’s really high in amino acids like glycine, which actually supports liver detox,” he says. “I add lots of vegetables and even green apples.” Find out more about the only cleanse diet that nutritionists approve of. One process by which the body eliminates toxins is enzymatic detoxification in the liver. A reliable biomarker for exposure to toxic chemicals is urinary D-glucaric acid. Such exposures induce the glucuronic acid enzymatic pathway and production of D-glucaric acid, thus urinary D-glucaric acid is an indirect byproduct of chemical exposure and phase I detoxification reactions.